Paul G Ambrose Selected Research

Bacterial Pneumonia

1/2020	Pharmacokinetic-Pharmacodynamic Characterization of Omadacycline against Haemophilus influenzae Using a One-Compartment In Vitro Infection Model.
1/2020	Population Pharmacokinetic Analyses for Omadacycline Using Phase 1 and 3 Data.
1/2020	Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Support Dose Selection for ME1100, an Arbekacin Inhalation Solution.
1/2019	Population Pharmacokinetic Analyses for Plazomicin Using Pooled Data from Phase 1, 2, and 3 Clinical Studies.
1/2019	Pharmacokinetic/pharmacodynamic target attainment analyses to support intravenous and oral lefamulin dose selection for the treatment of patients with community-acquired bacterial pneumonia.
1/2019	Pharmacokinetic/Pharmacodynamic Evaluation of Solithromycin against Streptococcus pneumoniae Using Data from a Neutropenic Murine Lung Infection Model.
1/2019	Population Pharmacokinetic Analyses for Arbekacin after Administration of ME1100 Inhalation Solution.
1/2019	Pharmacokinetic/Pharmacodynamic Evaluation of a Novel Aminomethylcycline Antibiotic, KBP-7072, in the Neutropenic Murine Pneumonia Model against Staphylococcus aureus and Streptococcus pneumoniae.
1/2018	Erratum for Drusano et al., "Dilution Factor of Quantitative Bacterial Cultures Obtained by Bronchoalveolar Lavage in Patients with Ventilator-Associated Bacterial Pneumonia".
1/2018	Dilution Factor of Quantitative Bacterial Cultures Obtained by Bronchoalveolar Lavage in Patients with Ventilator-Associated Bacterial Pneumonia.

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Paul G Ambrose Research Topics

Disease

54	Infections 11/2021 - 03/2002
13	Bacterial Pneumonia 01/2020 - 08/2010
12	Body Weight (Weight, Body) 01/2019 - 03/2006
8	Pneumonia (Pneumonitis) 01/2019 - 03/2002
6	Respiratory Tract Infections (Respiratory Tract Infection) 01/2019 - 01/2003
5	Urinary Tract Infections (Urinary Tract Infection) 01/2020 - 04/2006
5	Bacteremia 12/2015 - 03/2006
3	Communicable Diseases (Infectious Diseases) 07/2020 - 01/2017
3	Tuberculosis (Tuberculoses) 11/2018 - 01/2007
3	Endocarditis 12/2015 - 06/2010
3	Healthcare-Associated Pneumonia 03/2012 - 12/2010
3	Maxillary Sinusitis 05/2008 - 06/2004
2	Pseudomonas Infections 01/2020 - 09/2009
2	Gonorrhea 01/2020 - 09/2008
2	Sepsis (Septicemia) 01/2019 - 03/2002
2	Critical Illness (Critically Ill) 01/2019 - 04/2009
2	Meningeal Tuberculosis (Tuberculous Meningitis) 11/2018 - 07/2011
2	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 11/2018 - 11/2018
2	Invasive Candidiasis 01/2018 - 05/2011
2	Candidemia 01/2018 - 05/2011
2	Candidiasis (Moniliasis) 01/2018 - 01/2018
2	Intraabdominal Infections 01/2017 - 07/2005
2	Cystic Fibrosis (Mucoviscidosis) 09/2014 - 09/2009
2	Diarrhea 01/2012 - 07/2005
2	Nausea 01/2012 - 07/2005
2	Headache (Headaches) 01/2012 - 07/2005
2	Cross Infection (Nosocomial Infection) 09/2008 - 04/2006
2	Torsades de Pointes (Torsade de Pointes) 07/2005 - 05/2002
2	Bacterial Infections (Bacterial Infection) 07/2005 - 03/2002
2	Blister (Bulla) 07/2005 - 01/2005
1	Pyelonephritis 01/2019
1	Invasive Pulmonary Aspergillosis 01/2019
1	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 04/2012
1	Anthrax 04/2012
1	Clostridium Infections 04/2012

Drug/Important Bio-Agent (IBA)

20	Pharmaceutical PreparationsIBA 01/2020 - 05/2002
11	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 08/2003
8	Anti-Infective Agents (Microbicides)IBA 07/2020 - 07/2005
6	Levofloxacin (Levaquin)FDA Link 11/2018 - 01/2003
6	Tigecycline (Tygacil)FDA Link 03/2012 - 07/2005
5	Meropenem (Merrem)FDA LinkGeneric 01/2019 - 05/2010
5	QuinolonesIBA 09/2008 - 09/2003
4	Gatifloxacin (Zymar)FDA Link 11/2018 - 01/2003
4	Cefepime (Maxipime)FDA LinkGeneric 12/2017 - 03/2002
4	Tazobactam FDA LinkGeneric 12/2017 - 06/2013
4	oritavancinIBA 04/2012 - 01/2005
4	FluoroquinolonesIBA 07/2011 - 05/2002
3	gepotidacinIBA 11/2021 - 01/2017
3	SolutionsIBA 01/2020 - 12/2015
3	AminoglycosidesIBA 01/2020 - 01/2019
3	tazobactam drug combination ceftolozaneIBA 01/2018 - 09/2013
3	ceftolozaneIBA 12/2017 - 06/2013
3	Fosfomycin FDA Link 01/2017 - 12/2015
3	Ceftaroline FDA Link 01/2015 - 11/2013
3	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2015 - 04/2006
2	Colistin (Coly-Mycin)FDA Link 01/2020 - 01/2019
2	omadacyclineIBA 01/2020 - 01/2020
2	arbekacinIBA 01/2020 - 01/2019
2	APX001AIBA 01/2019 - 01/2018
2	ProdrugsIBA 01/2019 - 05/2010
2	EchinocandinsIBA 01/2018 - 05/2011
2	RezafunginIBA 01/2018 - 01/2018
2	Daptomycin FDA Link 12/2015 - 06/2010
2	Amikacin (A.M.K)FDA LinkGeneric 09/2014 - 09/2009
2	Penicillins (Penicillin)FDA Link 04/2012 - 01/2005
2	Fusidic Acid (Fucithalmic)IBA 06/2011 - 05/2011
2	beta-LactamsIBA 05/2010 - 01/2005
2	MacrolidesIBA 01/2008 - 01/2005
2	Isoniazid (Ftivazide)FDA LinkGeneric 07/2007 - 01/2007
2	GlycopeptidesIBA 03/2006 - 01/2005
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2020
1	Polymyxin B (Aerosporin)FDA LinkGeneric 01/2020
1	lefamulinIBA 01/2019
1	kbp-7072IBA 01/2019
1	apotransferrinIBA 01/2019
1	L 084IBA 01/2019
1	tebipenemIBA 01/2019
1	solithromycinIBA 01/2019
1	plazomicinIBA 01/2019
1	PleuromutilinsIBA 01/2019
1	Antifungal AgentsIBA 01/2019
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2019
1	Moxifloxacin (Avelox)FDA Link 11/2018
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2018
1	Ceftazidime (Fortum)FDA LinkGeneric 12/2017
1	LactamsIBA 12/2017
1	Topoisomerase InhibitorsIBA 01/2017
1	Piperacillin FDA LinkGeneric 04/2016
1	SaltsIBA 12/2015
1	Tromethamine (Trometamol)FDA Link 12/2015
1	Oseltamivir (Tamiflu)FDA Link 08/2013
1	Vancomycin FDA LinkGeneric 04/2012
1	cefilavancinIBA 03/2012

Therapy/Procedure

8	Therapeutics 01/2020 - 01/2005
6	Mechanical Ventilators (Ventilator) 01/2020 - 08/2010
2	Intravenous Administration 01/2018 - 04/2012
1	Duration of Therapy 01/2019
1	Intravenous Infusions 01/2019
1	Oral Administration 01/2018
1	Central Venous Catheters 04/2012